UCI Biomarker Detection Laboratory for
Early Detection Research Network (EDRN)
Publications
2010
Wang Y, Xia XQ, Jia Z, Sawyers A, Yao H, Wang-Rodriquez J, Mercola D, McClelland M. In silico estimates of tissue components in surgical samples based on expression profiling data. Cancer Res. 2010 Aug 15;70(16):6448-55. Epub 2010, Jul 27. PubMed PMID: 20663908
2011
Jia Z, Wang Y, Sawyers A, Yao H, Rahmatpanah F, Xia XQ, Xu Q, Pio R, Turan T, Koziol JA, Goodison S, Carpenter P, Wang-Rodriquez J, Simoneau A, Meyskens F, Sutton M, Lernhardt W, Beach T, Monforte J, McClelland M*, and MercolaD*. Diagnosis of Prostate Cancer Using Differentially Expressed Genes in Stroma. Cancer Res. 2011;71(7):2476-2487. PMID: 21459804. PCMID: PCM3071046. *Contributed equally
Major JM, Klonoff-Cohen HS, Pierce JP, Slymen DJ, Saltzstein SL, Macera, C, Mercola, D, Kattan MW. Prostate Cancer Postoperative Nomogram Scores and Obesity. PLoS ONE. 2011;6(2). PCMID: PCM3044730. (e17382. doi:10.1371/journal.pone.0017382).
Chen X, Xu S, Wang Y, McClelland M, Jia Z, and Mercola D. Identification of Biomarkers for Prostate Cancer Prognosis Using a Novel Two-Step Cluster Analysis, in "Pattern Recognition in Bioinformatics", M. Loog et al. (Eds.): PRIB 2011, LNBI 7036, pp. 63–74, 2011. Springer-Verlag Berlin Heidelberg 2011.
2012
Jia Z, Wang Y, Hu Y, McLaren C, Yu Y, Ye K, Xia XQ, Koziol JA, Lernhardt W, McClelland M, and Mercola D. A Sample Selection Strategy to Boost the Statistical Power of Signature Detection in Cancer Expression Profile Studies. Anti-Cancer Agents in Medicinal Chemistry 2012; Vol. 12: Epublication, August 24, 2012.(http://www.benthamscience.com/cmcaca/MSandI.htm). (http://www.ncbi.nlm.nih.gov/pubmed/22934703).
Jia Z, Rahmatpanah F, Chen X, Lernhardt W, Wang Y, Xia XQ, Sawyers A, McClelland M, and Mercola D. Expression changes in the stroma of prostate cancer predict subsequent relapse. PloS ONE 2012;7: Epublication August 3, 2012. PMID: 22870216. PMCID: PMC3411675.(Comments in: UroToday Oct. 19, 2012, http://www.urotoday.com/index.php?option=com_content&Itemid=792&catid=1137&id=54561&lang=en&view=article
Chen X, Xu S, Rahmatpanah F, McClelland M, Jia Z, and Mercola D. An accurate prostate cancer prognosticator using a seven-gene signature plus Gleason score derived by taking cell type-heterogeneity into account. PloS ONE, 2012;7(9) e45178. doi:10.1371/journal.pone.0045178. PMID: 23028830; [PMCID in process].
Khan S, Jutzy JM, Valenzuela MM, Turay D, Aspe JR, Ashok A, Mirshahidi S, Mercola D, Lilly MB, Wall NR. Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer. PLoS ONE. 2012;7(10):e46737. doi: 10.1371/journal.pone.0046737. Epub 2012 Oct 16. PubMed PMID: 23091600. PMCID in process].
Lee C, Zhang Q, Zi X, Dash A, Soares MB, Rahmatpanah F, Jia Z, McClelland M, Mercola D. TGF-β mediated DNA methylation in prostate cancer. Translational Andrology and Urology 2012;1(2):78-88. DOI: 10.3978/j.issn.2223-4683.2012.05.06.
Rahmatpanah F, Jia Z, Chen X, Jones FE, McClelland M, Mercola D. Expression of HER2 in Breast Cancer Promotes a Massive Reorganization of Gene Activity and Suggests a Role for Epigenetic Regulation. J Data Mining Genomics Proteomics. 2012:3 doi:pii: e102. PubMed PMID: 24009986; PubMed Central PMCID: PMC3760961. JDMGP an open access journal.(http://www.omicsonline.org/2153-0602/2153-0602-3-e102.php?aid=10410)
2013
Pio R, Jia Z, Baron VT, and Mercola D. Early Growth Response Gene 3 (Egr3) is highly over-expressed in non-relapsing prostate cancer but not in relapsing prostate cancer. PloS ONE, 2013; 8: (in press).
Kinseth MA, Zhenyu Jia, Farahnaz Rahmatpanah, Anne Sawyers, Manuel Sutton, Jessica Wang-Rodriguez, Kathleen L. McGuire and Dan Mercola. Altered Gene Expression by Prostate Tumor and Stroma in African American and Cell-type Matched Caucasians Reveal that Stroma is the Site of Aggressive Changes. Int. J. Cancer, Online June 10, 2013, DOI: 10.1002/ijc.28326. (notice in MDLinx.com: http://www.mdlinx.com/oncology/news-article.cfm/4669757).
Chung Lee, Qiang Zhang, James Kozlowski, Charles Brendler, Marcelo B. Soares, Atrya Dash, Michael McClelland, and Dan Mercola, Natural products and transforming growth factor-beta (TGF-β) signaling in cancer development and progression. Curr Cancer Drug Targets. 2013; 13(5): 500-5. PMID:23597196.
Xuejiao Tian, Saiyang Zhang, Hong-Min Liu, Yan-Bing Zhang, Christopher A Blair, Dan Mercola, Paolo Sassone-Corsi and Xiaolin Zi. Histone Lysine-Specific Methyltransferases and Demethylases in Carcinogenesis: New Targets for Cancer Therapy and Prevention Current Cancer Drug Targets, 2013;13:558-579. PMID 23713993.
Submitted Manuscripts
Zhenyu Jia, Michael Lilly, James A. Koziol, Xin Chen, Xiao-Qin Xia, Yipeng Wang, Douglas Skarecky, Herb Ruckle, Philip Carpenter, Jessica-Wang Rodriquez, Michael Kattan, Thomas Ahlering, and Dan Mercola. A method for generation of virtual controls for single arm prostate cancer adjuvant trials with application to a high risk cohort. (The Prostate).