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Molecular Diagnostics Laboratory

DiagnosticMolecularThe Molecular Diagnostics Laboratory at UC Irvine Medical Center uses a wide range of techniques including PCR, Southern blot analysis, microarrays and DNA sequencing to perform testing for hereditary disorders, pharmacogenomics, cancer diagnosis and management.

The laboratory provides testing services for UC Irvine Medical Center and for other hospitals and research investigators involved in clinical studies.

Services are available in the following areas. [Test code]:

  • Acute Myeloid-10 Gene Panel by Next Generation Sequencing [AML10]
  • BCR-ABL1 Qualitative Test [BAQUAL]
  • BCR-ABL1 P210 IVDA Quantitative qPCR Test [BCR210]
  • BCR-ABL1 P190 Quantitative Mutation Test [BCR190]
  • BRAF gene mutation detection for colorectal cancer and melanoma [BRAFC or BRAFM]
  • Calreticulin Exon 9 Mutation [CALR]
  • Colorectal Panel by Next Generation Sequencing [NGSCOL]
  • EGFR gene mutation detection for non-small cell lung cancer [EGFR]
  • Factor V Leiden mutation detection [VLEID]
  • FLT3 ITD and TKD Mutation assay [FLT3]
  • Prothrombin 20210A mutation detection [IIVAR]
  • MTHFR mutation detection [MTHFR]
  • Hereditary hemachromatosis mutation analysis [HFE]
  • JAK2 mutation detection (for myeloproliferative neoplasms) [JAK2]
  • CYP2C19 gene mutation analysis [2C19]
  • Microsatellite instability analysis (for colorectal cancer) [MSI]
  • UGT1A1 promoter polymorphism analysis (Irinotecan) [UGT1A1]
  • APOE E4 genotype analysis [APOEP]

Personalized Medicine

Educational opportunities include:


Jeff Chan
Jeff Chan, MD, PhD
Co-Medical Director,
Molecular Pathology

Robert Edwards
Robert A. Edwards, MD, PhD
Co-Medical Director,
Molecular Pathology

Contact Information

Location and General Inquiries
UC Irvine Health
Building 54
101 The City Drive South
Orange, CA 92868
Phone: 714-456-6141
Fax: 714-456-5873

Pathology Requests and Reports
Lab Business Hours: Monday-Friday 8:30 am to 5:00 pm
Phone: 714-456-5410

Jeff Chan, MD, PhD
Robert Edwards, MD, PhD
Phone: 714-456-5422

Laboratory Supervisor
Ellen Aquino
Phone: 714-456-5422


For more information, call 1-888-UCI-LABS (888-824-5227)