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Ophthalmic Pathology

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Ophthalmic pathology is concerned with the diagnosis of cytological and tissue specimens from the eye and orbit. Our physicians process and interpret surgical, cytology and autopsy specimens, with special interest in ocular and orbital lesions including lacrimal gland neoplasms and fine-needle aspiration of tumors in the eye and orbital socket.

Services are available in the following areas:

  • Consultation services for problematic and unusual cases
  • Resection and biopsy reviews
  • Biopsies from the eye and eyelids
  • Cytologic specimens from the eye and orbit, including fine-needle aspiration
  • Consultation services for examination of enucleation and exenteration specimens

Educational opportunities include:

  • Residency training
  • Conferences bi-weekly at UC Irvine Medical Center or Gavin Herbert Eye Institute


  • Application of molecular diagnostics in neoplasms of the ocular surface and periocular region
  • Analysis of the pathogenesis of melanocytic lesions of the conjunctiva
  • Mechanisms involved in infectious diseases of the eye and ocular adnexal structures
  • UV-related lesions of the ocular surface


Maria Del Valle Estopinal
Maria Del Valle Estopinal, MD
Medical Director,
Ophthalmic Pathology

Contact Information

Location and General Inquiries
UC Irvine Health
Douglas Hospital
101 The City Drive South
Orange, CA 92868-4805
Phone: 714-456-6141
Fax: 714-456-5873

Pathology Requests and Reports
Phone: 714-456-6141

Medical Director
Maria Del Valle Estopinal, MD



For more information, call 1-888-UCI-LABS (888-824-5227)